RNAi services: synthesis, chem modification, tissue targeting
Liposome formulation, siRNA liposome encapsulation
ELISA and cell-based assay development
Pharmaceuticals testing in vitro and in vivo, IC50 assays
Over 50 validated xenograft models
Stem cells isolation, characterization, and cell bank services
Generation of stable cell lines (protein overexpression) in 28 days
Generation of stable RNAi cell lines targeting gene of interest
Genome-wide library screening (small molecule, siRNA, miRNA)
In Vitro siRNA test (100+ cell lines/primary cultures available)
DNA and RNA isolation and purification
Cell-based assays: cytotoxicity, apoptosis, cell cycle arrest, etc
Protein services
Xenograft animal models CRO service
Transient and stable transfection services
siRNA, shRNA, miRNA design and synthesis
Liposome encapsulation service of RNA, DNA, and proteins
Oligonucleotide (siRNA) chemical modification: in vivo
Endotoxin and RNase contamination testing
Quantitation of gene silencing by qRT-PCR and Western Blot
GLP-compliant cell bank construction and cryopreservation
Custom reporter gene assays
Devolopment of in vivo transfection kits and reagents
In Vivo siRNA delivery and tissue targeted siRNA development
Altogen Labs (formerly Altogen Services) is located in Austin, Texas and provides life science research services to pharmaceutical, biotechnology, and academic research institutions worldwide. Altogen offers a complete solution for RNAi (gene silencing) projects, generation of stable cell lines, cloning, protein expression, reporter assay development, cell culture, transient and stable transfection, functional library screening (siRNA and microRNA), and various other biology, pharmacology, and toxicology (IND) services.
Altogen scientists bring years of experience and expertise to pre-clinical studies, as well as cell and molecular biology and RNAi projects. Altogen Services offers a wide range of custom research services to meet the unique needs of clients. Our technical support and quality control teams ensure and support our high-quality products and services.