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EpiMelt Assay Specific Controls
Epigenetic services | Customer Tailored Services
Combined EpiMelt Assay + EpiMelt MS-HRM PCR Master Mix
DNA Methylation is one of the most widely studied epigenetic mechanisms of gene expression regulation. Aberrant methylation of increasing number of genes is being shown to contribute to the majority of diseases such as cancer, cardiovascular disorders, aging, obesity, allergy, diabetes, depression, Alzheimer’s, Parkinson’s or schizophrenia.
Solid research evidence already shows that DNA methylation-based biomarkers can be utilized at all stages of clinical disease management including:
Disease risk assessment
Early detection
Personalization of treatment
Monitoring of chronic disorders and recurrence
The technology is already in use for detection of DNA methylation biomarkers in fields like forensics, and for investigating challenging DNA materiel sources as liquid biopsies and FFPE tissues.
MethylDetect offers ready-to-use kits for detection of aberrant gene methylation. The kits are based on the MS-HRM (Methylation Sensitive High Resolution Melting) technology and can be used with standard laboratory equipment. Additionally, our new controls system shipped with each kit, provides state-of-the-art experimental reliability.